Endothelin Polymorphisms as a Risk Factor for Cerebral Aneurysm Rebleeding Following Aneurysmal Subarachnoid Hemorrhage

Aneurysmal subarachnoid hemorrhage (aSAH) represents a unique form of hemorrhagic stroke due to rupture of an intradural cerebral aneurysm and is associated with high rates of morbidity and mortality. Considerable variation in the annual incidence of aSAH exists among different regions of the world with an incidence ranging from 2 to 16 cases per 100,000 [1,2]. Following the diagnosis of aSAH, early surgical or endovascular treatment of the aneurysm is recommended to reduce the rate of aneurysm rerupture [2].

Source: Clinical Neurology and Neurosurgery - April 7, 2017 Category: Neurosurgery Authors: Paul M. Foreman, Robert M. Starke, Philipp Hendrix, Mark R. Harrigan, Winfield S. Fisher, Nilesh A. Vyas, Robert H. Lipsky, Minkuan Lin, Beverly C. Walters, Jean-Francois Pittet, Mali Mathru, Christoph J. Griessenauer Source Type: research