Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C2C12 myotubes

This study shows that hyperuricemia induces mitochondrial dysfunction and triglyceride accumulation in skeletal muscle. The findings may explain why hyperuricemia is an independent predictor of diabetes.

Source: Journal of Applied Physiology - April 11, 2017 Category: Physiology Authors: Maarman, G. J., Andrew, B. M., Blackhurst, D. M., Ojuka, E. O. Tags: RESEARCH ARTICLE Source Type: research