Pten facilitates epiblast epithelial polarization and proamniotic lumen formation in early mouse embryos

Conclusion: We conclude that Pten is required for proamniotic cavity formation by establishing polarity for epiblast cells to form a rosette that expands into the proamniotic lumen, rather than facilitating apoptosis to create the cavity. This article is protected by copyright. All rights reserved.
Source: Developmental Dynamics - Category: Molecular Biology Authors: Tags: Research Article Source Type: research