ATRX is a novel progesterone-regulated protein and biomarker of low developmental potential in mammalian oocytes

In conclusion, localisation of ATRX to the cumulus cell nuclei and oocyte chromatin, after IVM, is associated with poor oocyte quality and low developmental potential. Furthermore, ATRX is dynamically regulated in response to progesterone signalling.

Source: Reproduction - April 6, 2017 Category: Reproduction Medicine Authors: OShea, L. C., Daly, E., Hensey, C., Fair, T. Tags: Research Source Type: research