Pathobiology of Human Papillomaviruses in Human Immunodeficiency Virus – Infected Persons

There is a complex interrelationship between human papillomaviruses (HPV) and human immunodeficiency viruses (HIV) that has been recognized from the start of the HIV epidemic. Cervical cancer was used as a surveillance indicator for acquired immunodeficiency syndrome (AIDS) before definitive identification of the viral etiology of either condition were known. Careful epidemiologic studies combined with clinical and laboratory measures of HPV, HPV-associated disease, and HIV have helped us understand many aspects of the relationship between these two virus groups; however, questions remain.

Source: Seminars in Diagnostic Pathology - April 6, 2017 Category: Pathology Authors: Uma Krishnamurti, Elizabeth R. Unger Source Type: research