Whole transcriptome profiling of the human hippocampus suggests an involvement of the KIBRA rs17070145 polymorphism in differential activation of the MAPK signaling pathway

In conclusion, our results suggest that the effect of the WWC1 rs17070145 polymorphism on memory performance and Alzheimer's disease might be due to a differential regulation of the MAPK signaling, a key pathway involved in memory and learning processes. This article is protected by copyright. All rights reserved.

Source: Hippocampus - April 1, 2017 Category: Neurology Authors: I.S. Piras, J. Krate, I. Schrauwen, J.J. Corneveaux, G.E. Serrano, L. Sue, T.G. Beach, M.J. Huentelman Tags: Research Article Source Type: research