Dendritic cells and macrophages in bladder tumor microenvironment as predictors of response to bacillus Calmette–Guérin immunotherapy

Conclusion: The pretreatment level and location of TAMs and TIDCs in NMIUC influence the BCG treatment outcome. Patients with low infiltration experienced significantly lower rates of BCG treatment failure. These observations present new predictor biomarkers of the response to BCG immunotherapy that could affect the choice of treatment after validation in larger cohorts.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research