Are tumor necrosis factor-α and matrix metalloproteinase-9 able to induce basal cell degeneration and enhance tissue destruction in cutaneous lichen planus?

Conclusion: In CLP, TNF-α and MMP-9 are produced by active lymphocytes and altered keratinocytes. They may act in cyclical mechanism and are responsible for tissue destruction mainly in the active stage of this disease.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research