Diagnostic role of CD44 and desmoglein 3 in sinonasal inverted papilloma and associated squamous cell carcinoma

Conclusion: The current study reports for the first time the combined use of CD44 and DSG3 immunohistochemical expression in normal sinonasal mucosa, IP, and SCC on top of IP. CD44 is more sensitive for IP compared with DSG3, which is more sensitive in the detection of SCC on top of IP. Therefore, the combined use of both markers is of diagnostic value in these tumors.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research