The cerebrovascular response to lower-body negative pressure vs. head-up tilt

This study showed that the pronounced reduction in end-tidal Pco2 together with gravitational effects on the brain circulation lead to a larger decline in cerebral blood flow velocity in response to head-up tilt than during lower-body negative pressure. This should be taken into account when employing lower-body negative pressure as MRI-compatible alternative to orthostatic stress.

Source: Journal of Applied Physiology - April 5, 2017 Category: Physiology Authors: Bronzwaer, A.-S. G. T., Verbree, J., Stok, W. J., Daemen, M. J. A. P., van Buchem, M. A., van Osch, M. J. P., van Lieshout, J. J. Tags: RESEARCH ARTICLE Source Type: research