Evaluation of assays for quantification of DNA in canine plasma as an indirect marker of NETosis

ConclusionsBoth assays as modified in this study are suitable for measuring DNA in canine EDTA or citrate plasma. However, performance of the fluorescence assay was impacted by pigmentemia, and it was less sensitive than the ELISA in detecting the presence of nucleosome material in the plasma.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fvcp.12478

Source: Veterinary Clinical Pathology - April 3, 2017 Category: Veterinary Research Authors: Stephanie A. Smith, Corinne M. Lawson, Maureen A. McMichael, Katrina Jung, Mauria O'Brien, Ron Achiel Tags: Original Research Source Type: research