Alliin, a garlic organosulfur compound, ameliorates gut inflammation through MAPK ‐NF‐κB/AP‐1/STAT‐1 inactivation and PPARγ activation

Conclusion: Our results show that alliin ameliorates DSS‐induced ulcerative colitis and inhibits the inflammatory responses in LPS‐stimulated RAW264.7 cells partly through inhibiting ERK1/2‐, JNK‐/PPARγ–stimulated NF‐κB/AP‐1/STAT‐1 activations and p38‐induced STAT‐1 activation.This article is protected by copyright. All rights reserved

Source: Nahrung / Food - March 1, 2017 Category: Nutrition Authors: Limin Shi, Qinlu Lin, Xinhua Li, Ying Nie, Shuguo Sun, Xiyun Deng, Long Wang, Jun Lu, Yiping Tang, Feijun Luo Tags: Research Article Source Type: research