Cardiovascular disease: Thioredoxin lowers hypertension

Nature Reviews Drug Discovery 16, 240 (2017). doi:10.1038/nrd.2017.53 Author: Sarah Crunkhorn The development of long-lasting antihypertensive therapies represents a crucial unmet need. Hilgers et al. now report that mice overexpressing the redox protein thioredoxin (TRX) are protected from age-related hypertension. Furthermore, injection of aged mice with recombinant human TRX (rhTRX) lowered blood pressure to levels
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research