A new MICA allele, MICA*007:07, characterized by cloning and sequencing

Summary A new MICA allelic variant, MICA*007:07, was identified in an individual of Mongol ethnicity in the Inner Mongolia Autonomous Region, northern China. Following polymerase chain reaction‐sequence‐based typing (PCR‐SBT), this new allele was further confirmed by cloning and sequencing. MICA*007:07 differs from MICA*007:01 by a synonymous mutation from G to A at the 2nd nucleotide position in exon 2. MICA*007:07 was linked to HLA‐B*27:05.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fiji.12311

Source: International Journal of Immunogenetics - March 29, 2017 Category: Genetics & Stem Cells Authors: W. Y. Wang, W. Tian, F. Wang, F. M. Zhu, P. X. Wang, L. F. Xing Tags: SHORT COMMUNICATION Source Type: research

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