Immune regulation by glucocorticoids

Nature Reviews Immunology 17, 233 (2017). doi:10.1038/nri.2017.1 Authors: Derek W. Cain & John A. Cidlowski Endogenous glucocorticoids are crucial to various physiological processes, including metabolism, development and inflammation. Since 1948, synthetic glucocorticoids have been used to treat various immune-related disorders. The mechanisms that underlie the immunosuppressive properties of these hormones have been intensely scrutinized, and it is widely appreciated that
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research