Combination of growth pattern and tumor regression identifies a high risk group in neoadjuvant treated rectal cancer patients

ConclusionLoss of E‐cadherin protein expression in the pretherapeutic biopsy of rectal cancer is associated with fewer metastases and improved survival. Furthermore the growth pattern in the post‐RCT resection specimen has a prognostic value for survival. A combination of growth pattern and tumor regression score (RegPat‐Score) showed the highest discriminatory power to identify high‐risk patients. Copyright © 2017 John Wiley & Sons, Ltd.

Source: Journal of Digestive Diseases - March 25, 2017 Category: Gastroenterology Authors: Jonas Jessberger, Katharina Erlenbach ‐Wünsch, Rebecca Posselt, Marlen Haderlein, Abbas Agaimy, Rainer Fietkau, Arndt Hartmann, Luitpold Distel Tags: Original Article Source Type: research