The role of interleukin 10 in human papilloma virus infection and progression to cervical carcinoma

Several viruses are capable of transforming infected cells into benign or malignant tumor cells, stimulating cell growth and survival by a wide range of mechanisms. Different oncogenic DNA viruses present this ability, including Human Papillomavirus (HPV), which is a well-established cause of squamous intraepithelial lesions (SIL) and cervical cancer [1,2]. Some HPV early oncoproteins are strictly correlated with cervical cancer initiation and progression, showing tumor-promoting activities [3].
Source: Cytokine and Growth Factor Reviews - Category: Molecular Biology Authors: Tags: Survey Source Type: research