Valproate and paliperidone interaction

Antiepileptic drugs are frequently used in the management of psychiatric conditions, particularly bipolar disorder. Since most psychotropic agents and antiepileptic drugs share the same metabolic pathways for elimination, there is a high likelihood of interactions between these two groups of drugs. Investigators recently examined the interaction potential between valproate and the atypical antipsychotic paliperidone in healthy volunteers and in patients with psychiatric disorders.

Source: The Brown University Psychopharmacology Update - March 23, 2017 Category: Psychiatry Authors: Y. W. Francis Lam Tags: Drug ‐Drug Interactions Source Type: research