Targeting neoantigens to augment antitumour immunity

Nature Reviews Cancer 17, 209 (2017).
doi:10.1038/nrc.2016.154

Authors: Mark Yarchoan, Burles A. Johnson, Eric R. Lutz, Daniel A. Laheru & Elizabeth M. Jaffee
The past decade of cancer research has been marked by a growing appreciation of the role of immunity in cancer. Mutations in the tumour genome can cause tumours to express mutant proteins that are tumour specific and not expressed on normal cells (neoantigens). These neoantigens

Source: Nature Reviews Cancer - February 24, 2017 Category: Cancer & Oncology Authors: Mark Yarchoan Burles A. Johnson Eric R. Lutz Daniel A. Laheru Elizabeth M. Jaffee Tags: Review Source Type: research