Quantifying the shifting landscape of B cell immunodominance
Nature Immunology 18, 367 (2017).
doi:10.1038/ni.3695
Authors: Gordon A Dale, Jessica R Shartouny & Joshy Jacob
Antibodies to neutralizing epitopes on hemagglutinin exhibit reproducible dynamic immunodominance patterns over time. Early responses target largely the Cb site, followed by Sb dominance and a concomitant rise in the diversity of neutralizing-antibody specificities.
Source: Nature Immunology - Category: Allergy & Immunology Authors: Gordon A Dale Jessica R Shartouny Joshy Jacob Tags: News and Views Source Type: research
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