Cell signalling: Notch under tension

Nature Reviews Molecular Cell Biology 18, 213 (2017). doi:10.1038/nrm.2017.29 Author: Paulina Strzyz Notch signalling is a conserved pathway that regulates cell fate decisions and is initiated by binding of a transmembrane ligand (Jagged (JAG) or Delta-like (DLL)) to a Notch receptor. This binding is followed by proteolytic cleavage of the receptor, which requires molecular tension. Building on
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Research Highlight Source Type: research