Contribution of neuroinflammation to changes in [11C]flumazenil binding in the rat brain: evaluation of the inflamed pons as reference tissue

This study aims to evaluate whether inflammatory processes in the brain can influence [11C]flumazenil uptake and affect the outcome of pharmacokinetic modeling when the pons is used as reference tissue.

Source: Nuclear Medicine and Biology - March 17, 2017 Category: Nuclear Medicine Authors: Andrea Parente, David V állez García, Alexandre Shoji, Isadora Lopes Alves, Bram Maas, Rolf Zijlma, Rudi AJO Dierckx, Carlos A Buchpiguel, Erik FJ de Vries, Janine Doorduin Source Type: research