Increased Nucleus Accumbens Volume in First-Episode Psychosis

Nucleus accumbens has been reported as a key structure in the neurobiology of schizophrenia. Studies analyzing structural abnormalities have shown conflicting results, possibly related to confounding factors. We investigated the nucleus accumbens volume using manual delimitation in first-episode psychosis (FEP) controlling for age, cannabis use and medication. Thirty-one FEP subjects who were naive or minimally exposed to antipsychotics and a control group were MRI scanned and clinically assessed from baseline to 6 months of follow-up.

Source: Psychiatry Research: Neuroimaging - March 17, 2017 Category: Psychiatry Authors: Mireia Forns-Nadal, Daniel Berg é, Federico Sem, Anna Mané, Laura Igual, Dani Guinart, Oscar Vilarroya Source Type: research