Synaptic plasticity: Kainate receptors can LTP

Nature Reviews Neuroscience 18, 194 (2017). doi:10.1038/nrn.2017.34 Author: Sian Lewis Classical synaptic long-term potentiation (LTP) requires NMDA receptor (NMDAR) activation, which drives AMPA receptor (AMPAR) insertion into the postsynaptic membrane. Here, activation of kainate receptors (KARs) in rat CA1 neurons triggered an increase in postsynaptic AMPAR surface expression and potentiated AMPAR-mediated CA1 excitatory postsynaptic responses.

http://feeds.nature.com/~r/nrn/rss/current/~3/KgXqB3_asNc/nrn.2017.34

Source: Nature Reviews Neuroscience - March 1, 2017 Category: Neuroscience Authors: Sian Lewis Tags: Research Highlight Source Type: research

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