Sleep: Gaining sleep while losing synapses

Nature Reviews Neuroscience 18, 194 (2017). doi:10.1038/nrn.2017.33 Author: Sian Lewis It has been suggested that synaptic weakening occurs during sleep to counterbalance daytime synaptic strengthening. The authors found that sleep was associated with a reduction in the level of postsynaptic AMPA receptors compared with awake periods, indicating homeostatic scaling down. The mechanism involves expression of
Source: Nature Reviews Neuroscience - Category: Neuroscience Authors: Tags: Research Highlight Source Type: research