Integrated classification of inflammatory myopathies

Inflammatory myopathies comprise a multitude of diverse diseases, most often occurring in complex clinical settings. To ensure accurate diagnosis, multidisciplinary expertise is required. Here, we propose a comprehensive myositis classification that incorporates clinical, morphological and molecular data as well as autoantibody profile. This review focuses on recent advances in myositis research, in particular, the correlation between autoantibodies and morphological or clinical phenotypes that can be used as the basis for an ‘integrated’ classification system.

Source: Neuropathology and Applied Neurobiology - March 14, 2017 Category: Neurology Authors: Y. Allenbach, O. Benveniste, H ‐H. Goebel, W. Stenzel Tags: Review Source Type: research