Association of single nucleotide polymorphisms of CACNA1A gene in migraine

Conclusion: In our study, we could not find any polymorphism of CACNA1A gene in the selected patients. Instead the wild type of genotype was found in both patients and controls. This negative result presented here, implies that if the CACNA1A gene is involved in typical migraine (with and without aura), its contribution is very modest and therefore difficult to discern. Nevertheless, there are other genes that could be considered potential candidates for typical migraine susceptibility for which further research is needed.
Source: Indian Journal of Human Genetics - Category: Genetics & Stem Cells Authors: Source Type: research