Changes in muscle fiber contractility and extracellular matrix production during skeletal muscle hypertrophy

This study utilized a rat synergist ablation model to integrate changes in single muscle fiber contractility, extracellular matrix composition, activation of important signaling pathways in muscle adaption, and corresponding changes in the muscle transcriptome to provide novel insight into the basic biological mechanisms of muscle fiber hypertrophy.

Source: Journal of Applied Physiology - March 5, 2017 Category: Physiology Authors: Mendias, C. L., Schwartz, A. J., Grekin, J. A., Gumucio, J. P., Sugg, K. B. Tags: RESEARCH ARTICLE Source Type: research