Epilepsy prevalence and severity predictors in mri-identified focal cortical dysplasia

Focal cortical dysplasia (FCD) is a malformation of cortical development that typically presents with childhood epilepsy (Bl ümcke et al., 2011; Sarnat& Flores-Sarnat, 2014; Sisodiya et al., 2014). Of patients with epilepsy, 5-10% also have FCD (Bast et al., 2006; Leach et al., 2014a). In pediatric cohorts with severe focal epilepsy, such as surgical candidates with drug-resistant epilepsy, up to 50% of patients have magnetic resonance imaging (MRI) visible FCD (Bast et al., 2006; Leach et al., 2014a).

Source: Epilepsy Research - March 4, 2017 Category: Neurology Authors: Lauren M. Maynard, James L. Leach, Paul S. Horn, Christine G. Spaeth, Francesco T. Mangano, Katherine D. Holland, Lili Miles, Robert Faist, Hansel M. Greiner Source Type: research