Obesity-associated extracellular mtDNA activates central TGF{beta} pathway to cause blood pressure increase

In conclusion, circulating mtDNA in the brain employs neural TGFβ pathway to mediate a central inflammatory mechanism of obesity-related hypertension.

Source: AJP: Endocrinology and Metabolism - March 1, 2017 Category: Endocrinology Authors: Ale, A., Zhang, Y., Han, C., Cai, D. Tags: Research Article Source Type: research