Using Global Metabolomics to Identify Novel Biomarkers of Treatment-Associated Cognitive Impairment in Pediatric Acute Lymphoblastic Leukemia

Conclusion: We identified several novel CSF biomarkers of treatment-related cognitive impairment among pediatric ALL patients. These findings may translate to clinical improvements in the management of cognitive outcomes by introducing the opportunity to deliver targeted interventions to high-risk patients prior to detectable or irreversible cognitive impairment.

Source: Cancer Epidemiology Biomarkers and Prevention - February 28, 2017 Category: Cancer & Oncology Authors: Brown, A., Rodgers, C., Taylor, O., Moore, I., Hooke, M., Pan, W., Hockenberry, M., Scheurer, M., Lupo, P. Tags: ASPO 41st Annual Meeting Abstracts Source Type: research