Twist of fate for skeletal muscle mesenchymal cells

Nature Cell Biology 19, 153 (2017).
doi:10.1038/ncb3482

Authors: Natalya A. Goloviznina & Michael Kyba
Skeletal muscles are composed of different types of fibres. Can these be thought of as distinct lineages with specific lineage-restricted progenitors? A provocative study now proposes that mesenchymal cells expressing the transcription factor Twist2 act as myogenic progenitors with selective type IIb fibre-differentiation potential.

Source: Nature Cell Biology - February 27, 2017 Category: Cytology Authors: Natalya A. Goloviznina Michael Kyba Tags: News and Views Source Type: research