Progesterone/estradiol ratio < 0.25 on the day of human chorionic gonadotropin administration is associated with adverse pregnancy outcomes in prolonged protocols for in  vitro fertilization/intracytoplasmic sperm injection

It has been suggested that a progesterone/estradiol ratio (P/E2)  ≥ 1.0 on the day of human chorionic gonadotropin (hCG) administration indicates premature luteinization and might be associated with an adverse pregnancy; however, a lower limit of this ratio has not been determined. We aimed to identify a lower limit of P/E2 that correlates significantly with an increase in adverse pregnancies in patients undergoing a prolonged in vitro fertilization/intracytoplasmic sperm injection therapy.

Source: Taiwanese Journal of Obstetrics and Gynecology - January 31, 2017 Category: OBGYN Authors: Yuan Li, Keli Luo, Yi Tang, Ge Lin, Guangxiu Lu, Fei Gong Tags: Original Article Source Type: research