Aspirin and Risk of Multiple Myeloma in Adults: A Systematic Review and Meta-Analysis

Publication date: Available online 28 February 2017 Source:Leukemia Research Reports Author(s): Shing Fung Lee, Ting Ying Ng, Frank Chi Sing Wong, Stewart Yuk Tung Multiple myeloma is a relatively uncommon plasma cell malignancy. Preclinical and clinical studies have suggested that aspirin might modify the risk of multiple myeloma. We performed a systematic review and meta-analysis of studies to examine the association between regular aspirin use and risk of multiple myeloma. Five observational studies including 332,660 adults were evaluated. The pooled estimate had a hazard ratio of 0.90 (95% confidence interval = 0.58 − 1.39; P = 0.638). Odds ratios from the two case-control studies were similar. The findings demonstrated that there was no significant association between aspirin use and the risk of multiple myeloma.
Source: Leukemia Research Reports - Category: Hematology Source Type: research