Genetic Dissection of Five Ethnic Groups from Punjab, North-West India –A Study based on Autosomal Markers

The majority of human DNA polymorphisms can be divided into two categories: those based on nucleotide substitutions (commonly known as “SNPs”) and those based on presence or absence of one or more nucleotides (Insertion/Deletion) [1]. Alu insertion elements represent the largest family of Short Interspersed elements (SINEs) in humans and are named due to the presence of an AluI recognition site in the sequence. They are extensi vely distributed throughout the human genome representing ∼10% of the total nuclear DNA [2,3] and their genotyping is relatively simple and inexpensive with a direct PCR-electrophoresis approach [4].

Source: Legal Medicine - February 27, 2017 Category: Forensic Medicine Authors: Gagandeep Singh, Indu Talwar, Harkirat Singh Sandhu, Kawaljit Matharoo, A.J.S. Bhanwer Source Type: research