Negative Pressure Wound Therapy With Instillation (NPWTi) Better Reduces Post-debridement Bioburden in Chronically Infected Lower Extremity Wounds Than NPWT Alone
Conclusion: It has long been realized that NPWT does not make its greatest impact by bioburden reduction. Other work has demonstrated that debridement alone does not reduce wound bioburden by more than 1 Log. Wounds treated with NPWTi (in this case with quarter strength bleach instillation solution) had a statistically significant reduction in bioburden, while wounds treated with NPWT had an increase in bioburden over the 7 days.
Source: Journal of the American College of Certified Wound Specialists - Category: Dermatology Authors: S.G. Goss, J.A. Schwartz, F. Facchin, E. Avdagic, C. Gendics, J.C. Lantis Tags: Research Papers Source Type: research