Effect of methoxy group position on biological properties of 18F –labeled benzyl triphenylphosphonium cations
18F –labeled phosphonium cations targeting mitochondrial membrane potential would be promising for positron emission tomography (PET) myocardial perfusion imaging (MPI). The purpose of this study was to examine the influence of additional methoxy group and its different positions on myocardium uptake and pharmacokinetics properties of 18F–labeled benzyl triphenylphosphonium cations.
Source: Nuclear Medicine and Biology - Category: Nuclear Medicine Authors: Shuting Chen, Zuoquan Zhao, Ying Zhang, Wei Fang, Jie Lu, Xianzhong Zhang Source Type: research