SUMO and the robustness of cancer
Nature Reviews Cancer 17, 184 (2017).
doi:10.1038/nrc.2016.143
Authors: Jacob-Sebastian Seeler & Anne Dejean
Post-translational protein modification by small ubiquitin-like modifier (SUMO), termed sumoylation, is an important mechanism in cellular responses to stress and one that appears to be upregulated in many cancers. Here, we examine the role of sumoylation in tumorigenesis as a possibly necessary safeguard that protects
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Jacob-Sebastian Seeler Anne Dejean Tags: Review Source Type: research
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