Tumorigenesis: Fitness penalties of aneuploidy

Nature Reviews Cancer 17, 142 (2017). doi:10.1038/nrc.2017.9 Author: Sarah Seton-Rogers Sheltzer et al. find that single-chromosome gains can prevent tumorigenesis relative to genetically matched euploid cells, but that these aneuploid cells can evolve over time to have improved fitness.

http://feeds.nature.com/~r/nrc/rss/current/~3/apF9Eusj5SA/nrc.2017.9

Source: Nature Reviews Cancer - February 9, 2017 Category: Cancer & Oncology Authors: Sarah Seton-Rogers Tags: Research Highlight Source Type: research

More News: Cancer | Cancer & Oncology | Genetics