Global distribution of consanguinity and their impact on complex diseases: Genetic disorders from an endogamous population

Conclusion The present study revealed a higher incidence of certain diseases in consanguineous population with a high significant increase in the prevalence of common adult diseases such as diabetes mellitus, cancer, blood disorders, mental disorders, heart diseases, asthma, gastro-intestinal disorders, hypertension, hearing deficit, G6PD and common eye diseases. This confirms the role of genetic factors across the full spectrum of disease and not only for Mendelian disorders.
Source: Egyptian Journal of Medical Human Genetics - Category: Genetics & Stem Cells Source Type: research