Mitotic spindle assembly in animal cells: a fine balancing act

Nature Reviews Molecular Cell Biology 18, 187 (2017). doi:10.1038/nrm.2016.162 Authors: Suzanna L. Prosser & Laurence Pelletier The mitotic spindle has a crucial role in ensuring the accurate segregation of chromosomes into the two daughter cells during cell division, which is paramount for maintaining genome integrity. It is a self-organized and dynamic macromolecular structure that is constructed from microtubules, microtubule-associated proteins and
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research