Commentary: Prostate cancer screening —A long run for a short slide

Enthusiasm for cancer screening is rooted in the early 20th century Halstedian paradigm that cancer is a localized, curable disease, which left untreated, will eventually spread to distant sites and become lethal [1 –3]. However, the natural history of malignancy has proved to be far more variable, ranging from cancers that have already metastasized by the time of diagnosis to those that remain indolent throughout their natural history, or even regress. Digital rectal examination [4] and transrectal ultrasoun d (TRUS) were the first prostate cancer early detection tools.
Source: Seminars in Oncology - Category: Cancer & Oncology Authors: Source Type: research