Polymorphism in Cytochrome P450 2D6, Glutathione S-Transferases Pi 1 Genes, and Organochlorine Pesticides in Alzheimer Disease: A Case-Control Study in North Indian Population
Conclusion:
This study demonstrates that the GSTP1*B and *C allelic variants may be considered a candidate gene for AD. It can be suggested that although CYP2D6*4 polymorphism is not a risk of AD, the CYP2D6*4 and GSTP1 polymorphism may interact with β-HCH, dieldrin, and copper to influence the risk of AD.
Source: Journal of Geriatric Psychiatry and Neurology - Category: Genetics & Stem Cells Authors: Singh, N. K., Banerjee, B. D., Bala, K., Basu, M., Chhillar, N. Tags: Articles Source Type: research
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