Aortic Waveform Analysis to Individualize Treatment in Heart Failure [Original Article]

Conclusions— Increased aortic pressure wave pulsatility and greater decrease in pulsatility on treatment are associated with functional improvement in patients with HF and reduced ejection fraction receiving aggressive vasodilator titration. These differences are not identifiable using brachial cuff pressures. Central aortic waveform analysis may enable better individualization of vasoactive therapies in chronic HF and reduced ejection fraction. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00588692.

http://circheartfailure.ahajournals.org/cgi/content/short/10/2/e003516?rss=1

Source: Circulation: Heart Failure - February 2, 2017 Category: Cardiology Authors: Wohlfahrt, P., Melenovsky, V., Redfield, M. M., Olson, T. P., Lin, G., Abdelmoneim, S. S., Hametner, B., Wassertheurer, S., Borlaug, B. A. Tags: Heart Failure, Hypertension Original Article Source Type: research