Identification of SNP-SNP interaction for chronic dialysis patients

This study proposes an effective algorithm named dynamic center particle swarm optimization k-nearest neighbors (DCPSO-KNN) to detect the SNP-SNP interaction. DCPSO-KNN uses dynamic center particle swarm optimization (DCPSO) to generate SNP combinations with a fitness function designed using the KNN method and statistical verification.

Source: Computers in Biology and Medicine - February 15, 2017 Category: Bioinformatics Authors: Cheng-Hong Yang, Zi-Jie Weng, Li-Yeh Chuang, Cheng-San Yang Source Type: research