Things that bug me 3 – vanc and pip/tazo

This study shows clearly that vanc & pip/tazo have a negative synergistic impact on the kidney.  The most interesting point in the article (to me) is that vanc trough levels predict AKI in vanc/cefepime but NOT in vanc/pip-tazo. So in 2017 I fear vanc/pip-tazo.  Patients on this combination had a length of stay averaging 2 days longer! The housestaff with whom I work know my fear, and work hard to avoid the combination.  Perhaps they are actually being more thoughtful about antibiotic choices.  That would be good for our patients.
Source: DB's Medical Rants - Category: Internal Medicine Authors: Tags: Medical Rants Source Type: blogs