Immunohistochemical methods as an aid in estimating the time since death

Morphological methods for time since death estimation are thought to be of no practical value in forensic practice. Although a comprehensive evaluation of all histologically, histochemically and electron-microscopically detectable postmortem changes shows that human tissues and organs decompose and break down in a certain sequence, in practice this sequence can be difficult to recognize, or not be seen at all in some cases. Laboratory experiments with artificial autolysis have shown that under precise conditions it is possible to histologically and histochemically establish the course of the first 48hours of this process [1].
Source: Forensic Science International - Category: Forensic Medicine Authors: Source Type: research