C18 ‐COOH Silica: Preparation, Characterisation and Its Application in Purification of Quaternary Ammonium Alkaloids from Coptis chinensis

ConclusionA multi‐functionalised silica was synthesised via “click chemistry”. As the high‐performance liquid chromatographic stationary phase, the C18‐COOH silica could be operated in trimodal reversed‐phase/weak cation exchange/hydrophilic interaction mode. The C18‐COOH silica also exhibited potential as solid‐phase extraction sorbent in the purification of quaternary ammonium alkaloids from complex matrices. Copyright © 2017 John Wiley & Sons, Ltd.

Source: Phytochemical Analysis - February 15, 2017 Category: Biochemistry Authors: Qing Wang, Yao Long, Lin Yao, Mao Ye, Li Xu Tags: Research Article Source Type: research