Nonmotor symptoms in de novo Parkinson disease comparing to normal aging

The Parkinson disease (PD) is one of the most common neurodegenerative brain disorders [1]. More recently, non-motor symptoms (NMS), such as psychiatric, sleep disorders, autonomic dysfunction symptoms and others, have been recognized as a potential cause of disability and deterioration of PD patients ’ quality of life [2–4]. NMS of PD occur throughout the disease course. There is evidence that certain NMS are present at disease onset or even may precede motor symptoms [5–8]. It has been suggested that some of the non-motor investigations could be added to support the diagnosis of Parkinson disease [8,9].

Source: Clinical Neurology and Neurosurgery - February 9, 2017 Category: Neurosurgery Authors: Petra Bago Ro žanković, Marjan Rožanković, Lovorka Vučak Novosel, Maristela Stojić Source Type: research