Defining precision: The precision medicine initiative TRIALS NCI-MPACT and NCI-MATCH

‘Precision′ trials, using rationally incorporated biomarker targets and molecularly selective anti-cancer agents, have become of great interest to both patients and their physicians. In the endeavor to test the cornerstone premise of precision oncotherapy, that is, determining if modulating a sp ecific molecular aberration in a patient′s tumor with a correspondingly specific therapeutic agent improves clinical outcomes, the design of clinical trials with embedded genomic characterization platforms which guide therapy are an increasing challenge.
Source: Current Problems in Cancer - Category: Cancer & Oncology Authors: Source Type: research